The following elements will have their visibility changed, please review the list before confirming the visibility change

Study

Study Name: Inflammatory infection and transmission of β-lactam resistance in a mouse model of ampicillin-induced microbiota

Projects

Biosamples

Organisms

Biosamples: 0 Seq. Projects: 18
STUDY INFORMATION
GOLD Study ID Gs0146776
Study Name Inflammatory infection and transmission of β-lactam resistance in a mouse model of ampicillin-induced microbiota
Other Names
NCBI Umbrella Bioproject Name
NCBI Umbrella Bioproject ID
SRA Studies
SRA Study Id SRP219110  (Link to NCBI )
Study Title Inflammatory infection and transmission of ß-lactam resistance in a mouse model of ampicillin-induced microbiota
Study Abstract
  
Legacy ER Study ID
Legacy GOLD ID
Added By JGI automated process on 2020-07-02
Last Modified By
PI
Description Humans and farm animals commonly consume food- or waterborne bacteria that harbour antibiotic resistance genes. The fate and potential horizontal gene transfer of those genes into the host microbiome will have a crucial bearing on the eventual health risk of exposure to antibiotic resistance genes. In the present study, the effects of antibiotics on the in vivo transfer of ??-lactam resistance genes were evaluated in a mouse model by characterizing the microbiome in excreted feces. Mice were dosed with Escherichia coli, Salmonella enterica serovars Heidelberg or Bredeney referred to as donors. The in vivo transfer of the antibiotic resistance genes (blaTEM-1B, blaCMY-2, blaCTX-M1, etc.) from these donor bacteria to an exogenously introduced or endogenously present Escherichia coli strains (i.e. recipients) in the mouse gut was evaluated with or without a clinical dosage of ampicillin.
Relevance
Study Information Link
Study Information Visibility Public
Metagenomic Study No
Publication
Is GEBA
Is HMP
ECOSYSTEM CLASSIFICATION
Ecosystem
Ecosystem Category
Ecosystem Type
Ecosystem Subtype
Specific Ecosystem
STUDY COMPOSITION
Number of Biosamples 0
Number of Organisms 18
Number of Seq Projects 18
Number of Analysis Projects 18
Number of Related Studies 0

 

 

  You are going to add the following user to ALL Sequencing Projects, Biosamples and Analysis Projects that
sit under this study (a cascading permission update).

 

Contact Name/Email:

Do you want to continue?

 

 

  You are going to remove permissions for the following user to all Sequencing Projects,
Biosamples and Analysis Projects under this study.

 

Contact Name/Email:

Do you want to continue?