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Study

Study Name: Clostridium botulinum BKT028387

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Biosamples

Organisms

Biosamples: 0 Seq. Projects: 1
STUDY INFORMATION
GOLD Study ID Gs0004205
Study Name Clostridium botulinum BKT028387
Other Names
NCBI Umbrella Bioproject Name
NCBI Umbrella Bioproject ID
SRA Studies
Legacy ER Study ID
Legacy GOLD ID
Added By Ionna Pagani on 2010-11-24
Last Modified By
PI
Description This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin. This toxin finds its use in various applications requiring neuroparalitic intervention, including cosmetology (Botox).
Relevance Food industry
Pharmaceutical
Medical
Study Information Link
Study Information Visibility Public
Metagenomic Study No
Publication
Is GEBA No
Is HMP No
ECOSYSTEM CLASSIFICATION
Ecosystem
Ecosystem Category
Ecosystem Type
Ecosystem Subtype
Specific Ecosystem
STUDY COMPOSITION
Number of Biosamples 0
Number of Organisms 1
Number of Seq Projects 1
Number of Analysis Projects 1
Number of Related Studies 0

 

 

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