| PROJECT INFORMATION | |
|---|---|
GOLD Project ID
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Gp0009013
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Project Name
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Clostridium botulinum BKT028387
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Other Names
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Legacy ER Project ID
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18373
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Legacy GOLD ID
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Gi08423
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| NCBI BioProject Name | Clostridium botulinum BKT028387 |
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NCBI BioProject ID
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60411 |
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NCBI BioProject Accession
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PRJNA60411 |
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NCBI Locus Tag
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CBC1
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NCBI BioSample Accession
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SAMN02470654 |
| PI | |
| Added By |
Ionna Pagani
on 2010-11-24 |
| Last Modified By |
JGI automated process
on 2014-10-31 |
| Project Comments |
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Project Status
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Permanent Draft
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Project Relevance
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Food industry Pharmaceutical Medical |
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Sequencing Center
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National Veterinary Institute (SVA), Sweden
(Sweden)
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Collaborating Institute
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Funding Agency
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Project Description
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This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin. This toxin finds its use in various applications requiring neuroparalitic intervention, including cosmetology (Botox).
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Project Information Visibility
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Public |
| PROJECT TYPE | |
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Specimen
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Organism |
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Nucleic Acid
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DNA |
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Sequencing Strategy
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Whole Genome Sequencing
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| EXTERNAL PROJECT LINKS | |
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Project Information
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Database
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Genome Publications
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Other Publications
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| PROJECT COMPOSITION | |
| Study |
Clostridium botulinum BKT028387 |
| Organism |
Clostridium botulinum BKT028387 |
| Analysis Projects |
Clostridium botulinum BKT028387 |
| Number of Analysis Projects |
1 |
| Number of DAPs |
0
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| SEQUENCING INFORMATION | |
|---|---|
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Sequencing Status
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Complete |
| Sequencing Quality (MIGS-31) |
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Finishing Goal
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Sequencing Comments
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Sequencing Technology
(MIGS-29)
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454 |
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Library Method
(MIGS-28)
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Number Of Reads
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Read Size
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Vector
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| GC Percent |
28
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| Chromosome Count |
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| Plasmid Count |
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| ORGANISM NAME | |
|---|---|
| GOLD Organism ID |
Go0009013 |
| Organism Name |
Clostridium botulinum BKT028387
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| Other names (alias, synonyms, short names, common names) |
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| Organism Domain |
BACTERIAL
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| Phylogeny |
FIRMICUTES
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| Genus |
Clostridium
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| Genus Synonyms |
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| Species |
Clostridium botulinum
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| Subspecies |
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| Species Synonyms |
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| Strain |
BKT028387
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| Strain Synonyms |
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| Serovar-Biovar |
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| Culture Collection ID |
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| Type Strain |
Unknown
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| Exemplar DOI |
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| Exemplar Name |
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| Taxon DOI |
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| Biosafety Level |
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| Organism Comments |
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| Cultured |
Yes
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| Culture Type |
Isolate
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| Organism Type |
Natural
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| Uncultured Type |
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| Commercial Strain |
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| Commercial Strain Comments |
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ORGANISM TAXONOMY
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| NCBI Taxonomy ID |
929507 |
| NCBI Superkingdom |
Bacteria
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| NCBI Kingdom |
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| NCBI Phylum |
Firmicutes
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| NCBI Class |
Clostridia
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| NCBI Order |
Clostridiales
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| NCBI Family |
Clostridiaceae
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| NCBI Genus |
Clostridium
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| NCBI Species |
Clostridium botulinum
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| ISOLATION CLASSIFICATION | |
| Ecosystem |
Host-associated
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| Ecosystem Category |
Birds
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| Ecosystem Type |
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| Ecosystem Subtype |
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| Specific Ecosystem |
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| ORGANISM EXTERNAL REFERENCES | |
| Strain Info ID |
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| Genbank 16S ID |
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| GENERAL PROPERTIES | |
|---|---|
| Oxygen Requirement |
Obligate anaerobe
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| Cell Shape |
Rod-shaped
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| Motility |
Motile
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| Sporulation |
Sporulating
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| Temperature Range |
Mesophile
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| Temperature Optimum |
37
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| Salinity |
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| pH |
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| Cell Diameter |
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| Cell Length |
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| Color |
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| Gram Staining |
Gram+
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| Biotic Relationships | Free living |
| Symbiotic Physical Interaction |
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| Symbiotic Relationship |
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| Symbiont Name |
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| Symbiont Taxon ID |
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| Cell Arrangements |
Singles Pairs |
| Diseases |
None |
| Known Habitats |
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| Metabolisms |
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| Phenotypes |
Non-Pathogen |
| Energy Sources |
Chemoorganotroph |
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