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Study

Study Name: Human fecal microbial communities from the University of Osaka, Japan, of patients with bacterial infections

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Biosamples

Organisms

Biosamples: 1 Seq. Projects: 1
STUDY NAME
GOLD Study ID Gs0059655
Study Name Human fecal microbial communities from the University of Osaka, Japan, of patients with bacterial infections
Other Names Metagenomic Diagnosis of Bacterial Infections
NCBI Umbrella Bioproject Name
NCBI Umbrella Bioproject ID
Legacy ER Study ID 14655
Legacy GOLD ID Gm00157
Added By Michelle Isbandi on 2009-03-08 00:00:00.0
Last Modified By Jyothi Mallajosyula on 2014-03-14 00:00:00.0
STUDY DESCRIPTION
PI Iida T
Description Infectious diseases are caused by various pathogens, including as-yet unidentifi ed microorganisms. Because procedures for detecting and identifying pathogens vary according to the target microorganism, clinical examinations require a variety of media, reagents, and culture methods. In addition, conventional examination protocols usually require much labor, time, and skill, thus forming an obstacle to a prompt diagnosis. Newly developed, "next-generation" DNA sequencers can determine >100 megabases of DNA sequences per run (1). These new technologies eliminate the bacterial cloning step used in traditional Sanger sequencing; instead, they amplify single isolated DNA molecules and analyze them with massively parallel processing. To develop a new system to promptly detect and identify various infectious pathogens, we tapped into the potential of these novel sequencers. We directly detected the causative pathogenic microbe in a clinical human sample (diarrheic feces) by means of unbiased high-throughput DNA sequencing.
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GOLD CLASSIFICATION
Ecosystem Host-associated
Ecosystem Category Human
Ecosystem Type Digestive system
Ecosystem Subtype Large intestine
Specific Ecosystem Fecal
Metagenomic Study Yes
STUDY COMPOSITION
Number of Biosamples 1
Number of Organisms 0
Number of Seq Projects 1
Number of Analysis Projects 0
Number of Related Studies 0

 

 

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