SRA STUDY
SRA Study Id ERP000089
Study Title Chlamydia trachomatis global diversity project
SRA Experiments
SRA Experiment Id ERX089038
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 4336262
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX089037
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 4336261
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX089036
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 4336260
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX089035
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 4336259
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX049758
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 3887923
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX140536
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 5341357
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX049756
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 3887921
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX049757
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 3887922
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX251538
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 6670788
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX140539
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 5341360
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX140538
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 5341359
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX089005
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 4203841
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX089004
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 4203840
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX089048
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 4336272
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX089047
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 4336271
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX089046
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 4336270
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX089045
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 4336269
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX116770
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 4601695
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX089000
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 4203836
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX116771
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 4601696
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX140540
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 5341361
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX019176
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 58062
Library Layout PAIRED
Library Instrument ILLUMINA_GENOME_ANALYZER_II
   
SRA Experiment Id ERX140542
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 5341363
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX088999
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 4203835
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX088997
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 4203833
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX251524
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 6670810
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX089007
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 4203843
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX089006
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 4203842
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX088996
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 4203832
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
   
SRA Experiment Id ERX251525
Exp Library Strategy WGS
Library Source GENOMIC
Library Selection RANDOM
Library Name 6670822
Library Layout PAIRED
Library Instrument ILLUMINA_HI_SEQ_2000
Study Abstract Chlamydia trachomatis is the most common cause of sexually transmitted infections in the UK, a statistic which is also reflected globally. There are two biovariants of C. trachomatis: trachoma and lyphogranuloma venereum (LGV). Trachoma isolates are non-invasive, whereas the LGV strains are invasive causing a disseminating infection of the local draining lymph nodes. Genome analysis has shown that the ocular and the genital trachoma isolates are 99.6 % identical at the sequence level and only show small differences in overall gene content. However, differences in coding potential, and the loss of function through point mutation, have been used to subdivide the trachoma strains into those associated with ocular and genital infections. We have previously sequenced a two LGV isolates; a long-term laboratory passaged strain and the recent ‘epidemic’ clinical LGV isolate causing proctitis. From these strains it was evident that there were no whole gene differences and that the recent epidemic isolate was a classical LGV isolate and has been circulating in the human population for a long time: an old strain causing a new disease. We have now put together a global collection of LGV isolates and are a sequencing them to determine the global phylogeny of this pathogen.. This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/
Alias Chlamydia trachomatis global diversity project
External Id PRJEB2035