PROJECT INFORMATION
GOLD Project ID
Gp0008491  
Project Name
Neisseria gonorrhoeae TCDC-NG08107  
Other Names
  
Legacy ER Project ID
18559  
Legacy GOLD ID
Gc01574  
NCBI BioProject Name Neisseria gonorrhoeae TCDC-NG08107
NCBI BioProject ID 61377
NCBI BioProject Accession PRJNA61377
NCBI Locus Tag
NGTW08  
NCBI BioSample Accession
PI Shu-Ying Li
Added By Ionna Pagani on 2011-01-12
Last Modified By Jon Bertsch on 2014-04-08
Project Comments
  
Project Status
Complete and Published  
Project Relevance Comparative analysis
Human Pathogen
Medical
Sequencing Center Centers for Disease Control and Prevention (CDC), USA (USA)
Collaborating Institute
  
Funding Agency
  
Project Description
One of two pathogenic Neisseria, this species causes the sexually transmitted disease (STD) gonorrhea, which is the leading reportable STD in adults in the USA. This human-specific organism colonizes and invades the mucosal surface of the urogenital epithelium, crosses the epithelial barrier, and ends up multiplying on the basement membrane. The result is severe painful inflammation and purulent discharge. Pathogenic functions include the antigenically variable type IV pilus and the opacity (Opa) proteins. The Opa proteins are responsible for the opaque colony phenotype due to the tight junctions between adjacent Neisseria, and are also responsible for tight adherence to host cells. This organism, like Neisseria meningitidis, is also naturally competent for DNA uptake.  
Project Information Visibility Public
PROJECT TYPE
Specimen Organism
Nucleic Acid DNA
Sequencing Strategy
Whole Genome Sequencing  
EXTERNAL PROJECT LINKS
Project Information
  
Database
  
Genome Publications Journal of bacteriology 193(7):1788-9 Draft genome sequence of a dominant, multidrug-resistant Neisseria gonorrhoeae strain, TCDC-NG08107, from a sexual group at high risk of acquiring human immunodeficiency virus infection and syphilis.
Other Publications
  
PROJECT COMPOSITION
Study Neisseria gonorrhoeae TCDC-NG08107
Analysis Projects Neisseria gonorrhoeae TCDC-NG08107
Number of Analysis Projects 1
Number of DAPs
0  
SEQUENCING INFORMATION
Sequencing Status Complete
Sequencing Quality (MIGS-31) Level 6: Finished
Finishing Goal
  
Sequencing Comments
  
Sequencing Technology (MIGS-29) Illumina GAIIx
454
Library Method (MIGS-28)
  
Number Of Reads
  
Read Size
  
Vector
  
GC Percent
52  
Chromosome Count
1  
Plasmid Count
1  
ORGANISM NAME
GOLD Organism ID Go0008491
Organism Name
Neisseria gonorrhoeae TCDC-NG08107  
Other names (alias, synonyms, short names, common names)
  
Organism Domain
BACTERIAL  
Phylogeny
PROTEOBACTERIA-BETA  
Genus
Neisseria  
Genus Synonyms
  
Species
Neisseria gonorrhoeae  
Subspecies
  
Species Synonyms
  
Strain
TCDC-NG08107  
Strain Synonyms
  
Serovar-Biovar
  
Culture Collection ID
  
Type Strain
Unknown  
Exemplar DOI
  
Exemplar Name
  
Taxon DOI
  
Biosafety Level
  
Organism Comments
  
Cultured
Yes  
Culture Type
Isolate  
Organism Type
Natural  
Uncultured Type
  
Commercial Strain
  
Commercial Strain Comments
  
ORGANISM TAXONOMY
NCBI Taxonomy ID 940296
NCBI Superkingdom
Bacteria  
NCBI Kingdom
  
NCBI Phylum
Proteobacteria  
NCBI Class
Betaproteobacteria  
NCBI Order
Neisseriales  
NCBI Family
Neisseriaceae  
NCBI Genus
Neisseria  
NCBI Species
Neisseria gonorrhoeae  
ISOLATION CLASSIFICATION
Ecosystem
Host-associated  
Ecosystem Category
Human  
Ecosystem Type
Unclassified  
Ecosystem Subtype
Unclassified  
Specific Ecosystem
Unclassified  
ORGANISM EXTERNAL REFERENCES
Strain Info ID
Genbank 16S ID
Synonym List
  
GENERAL PROPERTIES
Oxygen Requirement
Aerobe  
Cell Shape
Coccus-shaped  
Motility
Nonmotile  
Sporulation
Nonsporulating  
Temperature Range
Mesophile  
Temperature Optimum
  
Salinity
  
pH
  
Cell Diameter
  
Cell Length
  
Color
  
Gram Staining
Gram-  
Biotic Relationships Free living
Symbiotic Physical Interaction
  
Symbiotic Relationship
  
Symbiont Name
  
Symbiont Taxon ID
  
Cell Arrangements Pairs
Diseases Gonorrhea
Known Habitats Host
Metabolisms
  
Phenotypes Pathogen
Energy Sources
  

 

 

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