PROJECT NAME
GOLD Project ID
Gp0003458  
Project Name
Penicillium chrysogenum Wisconsin 54-1255  
Other Names
  
Legacy ER Project ID
98  
Legacy GOLD ID
Gi03056  
NCBI BioProject Name Penicillium chrysogenum Wisconsin 54-1255
NCBI BioProject ID 27927
NCBI BioProject Accession
PRJEA27927  
NCBI Locus Tag
PCH  
NCBI BioSample Accession
  
PI
Added By Nikos Kyrpides on 2008-03-30 00:00:00.0
Last Modified By Jyothi Mallajosyula on 2014-05-01 00:00:00.0
Project Comments
  
PROJECT TYPE
Specimen Organism
Nucleic Acid DNA
Sequencing Strategy
Whole Genome Sequencing  
PROJECT INFORMATION
Project Status
Permanent Draft  
Project Relevance Antibiotic production
Medical
Pharmaceutical
Sequencing Center DSM (Netherlands)
Collaborating Institute
  
Funding Agency
  
Project Description
Penicillium chrysogenum, also known as Penicillium notatum, is a filamentous asexual fungus with a relatively small genome. It has been used for over 60 years for the industrial production of penicillin, an antibiotic commonly used to treat bacterial infections. It is currently the primary commercial source of penicillinV and penicillinG. Strain improvement has resulted in increased productivity over the original isolates, mainly due to the amplification of a large genomic fragment containing the penicillin biosynthesis gene cluster. The biosynthesis of penicillin and the genes involved have been characterized in detail. P.chrysogenum has a haploid genome size of 34.1 Mb and distributed over four chromosomes.  
Project Information Visibility
Public  
EXTERNAL PROJECT LINKS
Project Information
  
Database
  
Genome Publications Nature biotechnology 26(10):1161-8 Genome sequencing and analysis of the filamentous fungus Penicillium chrysogenum.
Other Publications
  
Isolation Publications
  
NCBI SRA ID
  
PROJECT COMPOSITION
Studies Penicillium chrysogenum Wisconsin 54-1255
Analysis Projects Penicillium chrysogenum Wisconsin 54-1255
SEQUENCING INFORMATION
Sequencing Status Complete
Sequencing Quality (MIGS-31)
Finishing Goal
  
Sequencing Comments
  
Sequencing Technology (MIGS-29) Sanger
Library Method (MIGS-28)
Four plasmid libraries with inserts prepared by random shearing were constructed with insert sizes of 3?4 kb, 4?6 kb, 6?12 kb and 25?50 kb and 16000 clones from BACs  
Number Of Reads
  
Read Size
  
Vector
  
GC Percent
49  
Chromosome Count
  
Plasmid Count
  
ORGANISM NAME
GOLD Organism ID Go0003458
Organism Name
Penicillium chrysogenum Wisconsin 54-1255  
Other names (alias, synonyms, short names, common names)
  
Organism Domain
EUKARYAL  
Phylogeny
FUNGI-ASCOMYCOTA  
Genus
Penicillium  
Genus Synonyms
  
Species
Penicillium chrysogenum  
Subspecies
  
Species Synonyms
  
Strain
Wisconsin 54-1255  
Strain Synonyms
  
Serovar-Biovar
  
Culture Collection ID
  
Type Strain
Unknown  
Exemplar DOI
  
Exemplar Name
  
Taxon DOI
  
Biosafety Level
  
Organism Comments
  
Cultured
Yes  
Culture Type
Isolate  
Organism Type
Natural  
Uncultured Type
  
Commercial Strain
  
Commercial Strain Comments
  
ORGANISM TAXONOMY
NCBI Taxonomy ID 500485
NCBI Kingdom
Fungi  
NCBI Phylum
Ascomycota  
NCBI Class
Eurotiomycetes  
NCBI Order
Eurotiales  
NCBI Family
Aspergillaceae  
NCBI Genus
Penicillium  
NCBI Species
Penicillium rubens  
ISOLATION CLASSIFICATION
Ecosystem
Engineered  
Ecosystem Category
Unclassified  
Ecosystem Type
  
Ecosystem Subtype
  
Specific Ecosystem
  
ORGANISM EXTERNAL REFERENCES
Strain Info ID
Genbank 16S ID
Synonym List
  
GENERAL PROPERTIES
Oxygen Requirement
  
Cell Shape
  
Motility
  
Sporulation
  
Temperature Range
  
Temperature Optimum
  
Salinity
  
pH
  
Cell Diameter
  
Cell Length
  
Color
  
Gram Staining
  
Biotic Relationships
  
Symbiotic Physical Interaction
  
Symbiotic Relationship
  
Symbiont Name
  
Symbiont Taxon ID
  
Cell Arrangements
  
Diseases None
Known Habitats
  
Metabolisms Penicillin producer
Phenotypes
  
Energy Sources
  
CYANOBACTERIA METADATA
Filaments
  
Filament Type
  
Differentiated Cells
  
Position Of Heterocysts
  
Cysts
  
Mode Of Reproduction
  
Trichome
  
Trichome Type
  
Carotenoids
  
Pigments
  
Phage Infectivity
  
Phage Type
  
Restriction Enzyme
  
Toxin Production
  
Toxin Type
  
Secondary Metabolites
  
Developmental Cycle
  
Branching
  
Gas Vesicles
  
Gas Vesicle Type
  
Diagnostic Inclusion Body Information
  
Extracellular Structures
  
Bloom Forming
  
Pigment Type
  
Complementary chromatic adaptation (CCA)
  
Medium Types
  

 

 

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